Gene description for SPP1
Gene name secreted phosphoprotein 1
Gene symbol SPP1
Other names/aliases -
Species Bos taurus
 Database cross references - SPP1
ExoCarta ExoCarta_281499
Vesiclepedia VP_281499
Entrez Gene 281499
UniProt P31096  
 SPP1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SPP1
Molecular Function
    extracellular matrix binding GO:0050840 IEA
Biological Process
    ossification GO:0001503 IEA
    osteoblast differentiation GO:0001649 IEA
    cell adhesion GO:0007155 IEA
    positive regulation of bone resorption GO:0045780 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified SPP1 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SPP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SPP1 is involved
No pathways found





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