Gene description for SPP1
Gene name secreted phosphoprotein 1
Gene symbol SPP1
Other names/aliases -
Species Bos taurus
 Database cross references - SPP1
ExoCarta ExoCarta_281499
Entrez Gene 281499
UniProt P31096  
 SPP1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SPP1
Molecular Function
    cytokine activity GO:0005125 IEA
Biological Process
    biomineral tissue development GO:0031214 IEA
    cell adhesion GO:0007155 IEA
    ossification GO:0001503 IEA
Subcellular Localization
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified SPP1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SPP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SPP1 is involved
No pathways found





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