Gene description for SRPR
Gene name signal recognition particle receptor (docking protein)
Gene symbol SRPR
Other names/aliases -
Species Bos taurus
 Database cross references - SRPR
ExoCarta ExoCarta_281504
Entrez Gene 281504
UniProt Q3MHE8  
 SRPR identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SRPR
Molecular Function
    GTPase activity GO:0003924 IEA
    poly(A) RNA binding GO:0044822 IEA
    GTP binding GO:0005525 IEA
    signal recognition particle binding GO:0005047 IEA
Biological Process
    metabolic process GO:0008152 IEA
    SRP-dependent cotranslational protein targeting to membrane GO:0006614 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    signal recognition particle receptor complex GO:0005785 IEA
 Experiment description of studies that identified SRPR in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SRPR
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SRPR is involved
PathwayEvidenceSource
SRP-dependent cotranslational protein targeting to membrane IEA Reactome





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