Gene description for SVIL
Gene name supervillin
Gene symbol SVIL
Other names/aliases -
Species Bos taurus
 Database cross references - SVIL
ExoCarta ExoCarta_281509
Entrez Gene 281509
UniProt O46385  
 SVIL identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SVIL
Molecular Function
    actin filament binding GO:0051015 IEA
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of cytokinesis GO:0032467 IMP
    cytoskeleton organization GO:0007010 IEA
Subcellular Localization
    cell junction GO:0030054 IEA
    midbody GO:0030496 IDA
    invadopodium GO:0071437 IEA
    microtubule minus-end GO:0036449 IDA
    cytoplasm GO:0005737 IEA
    plasma membrane GO:0005886 IEA
    cleavage furrow GO:0032154 IDA
    podosome GO:0002102 IEA
 Experiment description of studies that identified SVIL in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SVIL
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SVIL is involved
No pathways found





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