Gene description for SVIL
Gene name supervillin
Gene symbol SVIL
Other names/aliases -
Species Bos taurus
 Database cross references - SVIL
ExoCarta ExoCarta_281509
Vesiclepedia VP_281509
Entrez Gene 281509
UniProt O46385  
 SVIL identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SVIL
Molecular Function
    phosphatidylinositol-4,5-bisphosphate binding GO:0005546 IEA
    actin filament binding GO:0051015 IEA
Biological Process
    cytoskeleton organization GO:0007010 IEA
    actin polymerization or depolymerization GO:0008154 IEA
    actin filament severing GO:0051014 IEA
    barbed-end actin filament capping GO:0051016 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    actin cytoskeleton GO:0015629 IEA
 Experiment description of studies that identified SVIL in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SVIL
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SVIL is involved
No pathways found





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