Gene description for WARS
Gene name tryptophanyl-tRNA synthetase
Gene symbol WARS
Other names/aliases -
Species Bos taurus
 Database cross references - WARS
ExoCarta ExoCarta_281576
Entrez Gene 281576
UniProt P17248  
 WARS identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for WARS
Molecular Function
    ATP binding GO:0005524 IEA
    tryptophan-tRNA ligase activity GO:0004830 IEA
Biological Process
    tryptophanyl-tRNA aminoacylation GO:0006436 IEA
    regulation of angiogenesis GO:0045765 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    extracellular exosome GO:0070062 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified WARS in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for WARS
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which WARS is involved
No pathways found





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