Gene description for WASL
Gene name Wiskott-Aldrich syndrome-like
Gene symbol WASL
Other names/aliases -
Species Bos taurus
 Database cross references - WASL
ExoCarta ExoCarta_281577
Entrez Gene 281577
UniProt Q95107  
 WASL identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for WASL
Molecular Function
    identical protein binding GO:0042802 IPI
    protein binding GO:0005515 IPI
    actin binding GO:0003779 IEA
Biological Process
    spindle localization GO:0051653 IEA
    regulation of protein localization GO:0032880 IEA
    negative regulation of membrane tubulation GO:1903526 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
    positive regulation of Arp2/3 complex-mediated actin nucleation GO:2000601 IEA
    cell division GO:0051301 IEA
    cellular protein complex localization GO:0034629 IEA
    response to bacterium GO:0009617 IEA
    mitotic nuclear division GO:0007067 IEA
    actin filament organization GO:0007015 IEA
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    actin cap GO:0030478 IEA
    extracellular exosome GO:0070062 IEA
    nucleus GO:0005634 IEA
    lamellipodium GO:0030027 IEA
    cytosol GO:0005829 IEA
 Experiment description of studies that identified WASL in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for WASL
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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