Gene description for ACTR3
Gene name ARP3 actin-related protein 3 homolog (yeast)
Gene symbol ACTR3
Other names/aliases -
Species Bos taurus
 Database cross references - ACTR3
ExoCarta ExoCarta_281597
Entrez Gene 281597
UniProt P61157  
 ACTR3 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ACTR3
Molecular Function
    actin filament binding GO:0051015 IEA
    structural constituent of cytoskeleton GO:0005200 IEA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
Biological Process
    meiotic cytokinesis GO:0033206 IEA
    establishment or maintenance of cell polarity GO:0007163 IEA
    spindle localization GO:0051653 IEA
    meiotic chromosome movement towards spindle pole GO:0016344 IEA
    Arp2/3 complex-mediated actin nucleation GO:0034314 IEA
    asymmetric cell division GO:0008356 IEA
    cilium morphogenesis GO:0060271 ISS
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    lamellipodium GO:0030027 IEA
    focal adhesion GO:0005925 IEA
    Arp2/3 protein complex GO:0005885 IEA
    cell-cell junction GO:0005911 IEA
    membrane GO:0016020 IEA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified ACTR3 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ACTR3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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