Gene description for ALDH1A1
Gene name aldehyde dehydrogenase 1 family, member A1
Gene symbol ALDH1A1
Other names/aliases ALDH1
Species Bos taurus
 Database cross references - ALDH1A1
ExoCarta ExoCarta_281615
Entrez Gene 281615
UniProt P48644  
 ALDH1A1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ALDH1A1
Molecular Function
    3-chloroallyl aldehyde dehydrogenase activity GO:0004028 IBA
    retinal dehydrogenase activity GO:0001758 IBA
    benzaldehyde dehydrogenase (NAD+) activity GO:0018479 IBA
Biological Process
    oxidation-reduction process GO:0055114 IEA
    retinol metabolic process GO:0042572 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified ALDH1A1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ALDH1A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ALDH1A1 is involved
PathwayEvidenceSource
Ethanol oxidation IEA Reactome
RA biosynthesis pathway IEA Reactome





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