Gene description for APOA1
Gene name	apolipoprotein A-I
Gene symbol	APOA1
Other names/aliases	-
Species	Bos taurus
Database cross references - APOA1
ExoCarta	ExoCarta_281631
Entrez Gene	281631
UniProt	P15497
APOA1 identified in exosomes derived from the following tissue/cell type
Milk	23459212
Serum	19327352

Gene ontology annotations for APOA1

Molecular Function     high-density lipoprotein particle receptor binding GO:0070653 IBA     beta-amyloid binding GO:0001540 IEA     identical protein binding GO:0042802 IEA     phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 IBA     cholesterol transporter activity GO:0017127 IBA     chemorepellent activity GO:0045499 IEA     cholesterol binding GO:0015485 IBA     phosphatidylcholine binding GO:0031210 IBA     high-density lipoprotein particle binding GO:0008035 IEA     apolipoprotein A-I receptor binding GO:0034191 IEA     enzyme binding GO:0019899 IEA Biological Process     positive regulation of cholesterol esterification GO:0010873 IBA     phospholipid efflux GO:0033700 IBA     phosphatidylcholine biosynthetic process GO:0006656 IEA     positive regulation of triglyceride catabolic process GO:0010898 IBA     positive regulation of transferase activity GO:0051347 IEA     integrin-mediated signaling pathway GO:0007229 IEA     negative regulation of very-low-density lipoprotein particle remodeling GO:0010903 IEA     negative regulation of hydrolase activity GO:0051346 IEA     protein stabilization GO:0050821 IEA     regulation of intestinal cholesterol absorption GO:0030300 IBA     phosphatidylcholine metabolic process GO:0046470 IBA     cholesterol biosynthetic process GO:0006695 IBA     negative regulation of cell adhesion molecule production GO:0060354 IEA     positive regulation of lipoprotein lipase activity GO:0051006 IBA     blood vessel endothelial cell migration GO:0043534 IEA     regulation of Cdc42 protein signal transduction GO:0032489 IEA     protein oxidation GO:0018158 ISS     reverse cholesterol transport GO:0043691 IBA     high-density lipoprotein particle assembly GO:0034380 IBA     lipoprotein biosynthetic process GO:0042158 IEA     glucocorticoid metabolic process GO:0008211 IEA     cholesterol import GO:0070508 IEA     very-low-density lipoprotein particle remodeling GO:0034372 IBA     positive regulation of stress fiber assembly GO:0051496 IEA     negative regulation of heterotypic cell-cell adhesion GO:0034115 IEA     positive regulation of fatty acid biosynthetic process GO:0045723 IBA     negative regulation of inflammatory response GO:0050728 IEA     negative regulation of tumor necrosis factor-mediated signaling pathway GO:0010804 IEA     negative regulation of interleukin-1 beta secretion GO:0050713 IEA     cholesterol homeostasis GO:0042632 IBA     peptidyl-methionine modification GO:0018206 ISS     endothelial cell proliferation GO:0001935 IEA     negative regulation of cytokine secretion involved in immune response GO:0002740 IEA     phospholipid homeostasis GO:0055091 IEA     positive regulation of substrate adhesion-dependent cell spreading GO:1900026 IEA     lipid storage GO:0019915 IEA     triglyceride catabolic process GO:0019433 IBA     G-protein coupled receptor signaling pathway GO:0007186 IEA     negative chemotaxis GO:0050919 IEA     adrenal gland development GO:0030325 IEA     cholesterol efflux GO:0033344 IBA     neuron projection regeneration GO:0031102 IBA     regulation of protein phosphorylation GO:0001932 IEA     positive regulation of Rho protein signal transduction GO:0035025 IEA     lipoprotein metabolic process GO:0042157 IBA     triglyceride homeostasis GO:0070328 IBA Subcellular Localization     very-low-density lipoprotein particle GO:0034361 IEA     spherical high-density lipoprotein particle GO:0034366 IEA     chylomicron GO:0042627 IBA     blood microparticle GO:0072562 IBA     endocytic vesicle GO:0030139 IEA     extracellular exosome GO:0070062 IEA     high-density lipoprotein particle GO:0034364 IBA