Gene description for CAPN2
Gene name calpain 2, (m/II) large subunit
Gene symbol CAPN2
Other names/aliases -
Species Bos taurus
 Database cross references - CAPN2
ExoCarta ExoCarta_281662
Entrez Gene 281662
UniProt Q27971  
 CAPN2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CAPN2
Molecular Function
    calcium ion binding GO:0005509 IEA
    calcium-dependent cysteine-type endopeptidase activity GO:0004198 ISS
Biological Process
    blastocyst development GO:0001824 IEA
    cellular response to amino acid stimulus GO:0071230 ISS
    regulation of cytoskeleton organization GO:0051493 IEA
    proteolysis GO:0006508 ISS
    myoblast fusion GO:0007520 IEA
Subcellular Localization
    focal adhesion GO:0005925 IEA
    nucleus GO:0005634 IEA
    chromatin GO:0000785 IEA
    pseudopodium GO:0031143 IEA
    Golgi apparatus GO:0005794 IEA
    cytoplasm GO:0005737 ISS
    membrane raft GO:0045121 IEA
    dendrite GO:0030425 ISS
    plasma membrane GO:0005886 IEA
    extracellular exosome GO:0070062 IEA
    perinuclear endoplasmic reticulum GO:0097038 IEA
    cytosol GO:0005829 IEA
 Experiment description of studies that identified CAPN2 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CAPN2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CAPN2 is involved
No pathways found

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