Gene description for EIF4E
Gene name eukaryotic translation initiation factor 4E
Gene symbol EIF4E
Other names/aliases -
Species Bos taurus
 Database cross references - EIF4E
ExoCarta ExoCarta_281751
Entrez Gene 281751
UniProt Q9N0T5  
 EIF4E identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for EIF4E
Molecular Function
    translation initiation factor activity GO:0003743 ISS
    poly(A) RNA binding GO:0044822 IEA
Biological Process
    G1/S transition of mitotic cell cycle GO:0000082 IEA
    translational initiation GO:0006413 IEA
    regulation of translation GO:0006417 ISS
    positive regulation of mitotic cell cycle GO:0045931 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    cytoplasmic stress granule GO:0010494 ISS
    cytoplasmic mRNA processing body GO:0000932 IEA
    chromatoid body GO:0033391 IEA
    cytoplasm GO:0005737 ISS
    mRNA cap binding complex GO:0005845 ISS
    RISC complex GO:0016442 IEA
    eukaryotic translation initiation factor 4F complex GO:0016281 ISS
 Experiment description of studies that identified EIF4E in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EIF4E
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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