Gene description for EIF4E
Gene name eukaryotic translation initiation factor 4E
Gene symbol EIF4E
Other names/aliases -
Species Bos taurus
 Database cross references - EIF4E
ExoCarta ExoCarta_281751
Entrez Gene 281751
UniProt Q9N0T5  
 EIF4E identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for EIF4E
Molecular Function
    translation initiation factor activity GO:0003743 ISS
    poly(A) RNA binding GO:0044822 IEA
Biological Process
    G1/S transition of mitotic cell cycle GO:0000082 IEA
    translational initiation GO:0006413 IEA
    regulation of translation GO:0006417 ISS
    positive regulation of mitotic cell cycle GO:0045931 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    cytoplasmic stress granule GO:0010494 ISS
    cytoplasmic mRNA processing body GO:0000932 IEA
    chromatoid body GO:0033391 IEA
    cytoplasm GO:0005737 ISS
    mRNA cap binding complex GO:0005845 ISS
    RISC complex GO:0016442 IEA
    eukaryotic translation initiation factor 4F complex GO:0016281 ISS
 Experiment description of studies that identified EIF4E in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EIF4E
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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