Gene description for B4GALT1
Gene name UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
Gene symbol B4GALT1
Other names/aliases GGTB2
Species Bos taurus
 Database cross references - B4GALT1
ExoCarta ExoCarta_281781
Entrez Gene 281781
UniProt P08037  
 B4GALT1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for B4GALT1
Molecular Function
    protein binding GO:0005515 IPI
    lactose synthase activity GO:0004461 ISS
    manganese ion binding GO:0030145 ISS
    N-acetyllactosamine synthase activity GO:0003945 ISS
    beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity GO:0003831 ISS
    beta-tubulin binding GO:0048487 ISS
    protein homodimerization activity GO:0042803 ISS
    alpha-tubulin binding GO:0043014 ISS
    UDP-galactosyltransferase activity GO:0035250 ISS
Biological Process
    cell adhesion GO:0007155 IEA
    lactose biosynthetic process GO:0005989 IEA
    branching morphogenesis of an epithelial tube GO:0048754 IEA
    oligosaccharide biosynthetic process GO:0009312 ISS
    regulation of cellular component movement GO:0051270 IEA
    binding of sperm to zona pellucida GO:0007339 IEA
    angiogenesis involved in wound healing GO:0060055 IEA
    penetration of zona pellucida GO:0007341 IEA
    acute inflammatory response GO:0002526 IEA
    mammary gland development GO:0030879 IEA
    leukocyte migration GO:0050900 IEA
    galactose metabolic process GO:0006012 IEA
    epithelial cell development GO:0002064 IEA
    positive regulation of apoptotic process involved in mammary gland involution GO:0060058 IEA
    extracellular matrix organization GO:0030198 IEA
    development of secondary sexual characteristics GO:0045136 IEA
    regulation of acrosome reaction GO:0060046 IEA
    positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 IEA
    negative regulation of cell proliferation GO:0008285 IEA
    protein N-linked glycosylation GO:0006487 ISS
Subcellular Localization
    brush border membrane GO:0031526 ISS
    Golgi trans cisterna GO:0000138 ISS
    extracellular exosome GO:0070062 IEA
    filopodium GO:0030175 IEA
    glycocalyx GO:0030112 ISS
    desmosome GO:0030057 ISS
    Golgi cisterna membrane GO:0032580 IEA
    integral component of membrane GO:0016021 IEA
    Golgi apparatus GO:0005794 ISS
    basolateral plasma membrane GO:0016323 ISS
    external side of plasma membrane GO:0009897 ISS
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified B4GALT1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for B4GALT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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