Gene description for GNA11
Gene name guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
Gene symbol GNA11
Other names/aliases -
Species Bos taurus
 Database cross references - GNA11
ExoCarta ExoCarta_281788
Entrez Gene 281788
UniProt P38409  
 GNA11 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GNA11
Molecular Function
    signal transducer activity GO:0004871 IBA
    G-protein beta/gamma-subunit complex binding GO:0031683 IBA
    type 2A serotonin receptor binding GO:0031826 IBA
    GTPase activity GO:0003924 IBA
    GTP binding GO:0005525 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    metabolic process GO:0008152 IEA
    heart development GO:0007507 IEA
    cellular response to pH GO:0071467 IEA
    phospholipase C-activating dopamine receptor signaling pathway GO:0060158 IBA
    regulation of melanocyte differentiation GO:0045634 IEA
    developmental pigmentation GO:0048066 IEA
    skeletal system development GO:0001501 IEA
    adenylate cyclase-modulating G-protein coupled receptor signaling pathway GO:0007188 IBA
    action potential GO:0001508 IBA
Subcellular Localization
    plasma membrane GO:0005886 TAS
    heterotrimeric G-protein complex GO:0005834 IBA
    extracellular exosome GO:0070062 IEA
    lysosomal membrane GO:0005765 IEA
 Experiment description of studies that identified GNA11 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GNA11
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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