Gene description for GNAI1
Gene name guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Gene symbol GNAI1
Other names/aliases -
Species Bos taurus
 Database cross references - GNAI1
ExoCarta ExoCarta_281790
Entrez Gene 281790
UniProt P63097  
 GNAI1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GNAI1
Molecular Function
    metal ion binding GO:0046872 IEA
    G-protein beta/gamma-subunit complex binding GO:0031683 IBA
    G-protein coupled serotonin receptor binding GO:0031821 IBA
    GTP binding GO:0005525 IEA
    GTPase activity GO:0003924 IBA
    signal transducer activity GO:0004871 IBA
Biological Process
    cell division GO:0051301 ISS
    metabolic process GO:0008152 IEA
    cell cycle GO:0007049 IEA
    adenylate cyclase-modulating G-protein coupled receptor signaling pathway GO:0007188 IBA
Subcellular Localization
    midbody GO:0030496 ISS
    centrosome GO:0005813 ISS
    heterotrimeric G-protein complex GO:0005834 IBA
    nucleus GO:0005634 IEA
    extracellular exosome GO:0070062 IEA
    lysosomal membrane GO:0005765 IEA
    plasma membrane GO:0005886 ISS
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified GNAI1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GNAI1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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