Gene description for GNAI1
Gene name guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Gene symbol GNAI1
Other names/aliases -
Species Bos taurus
 Database cross references - GNAI1
ExoCarta ExoCarta_281790
Entrez Gene 281790
UniProt P63097  
 GNAI1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GNAI1
Molecular Function
    metal ion binding GO:0046872 IEA
    G-protein beta/gamma-subunit complex binding GO:0031683 IBA
    G-protein coupled serotonin receptor binding GO:0031821 IBA
    GTP binding GO:0005525 IEA
    GTPase activity GO:0003924 IBA
    signal transducer activity GO:0004871 IBA
Biological Process
    cell division GO:0051301 ISS
    metabolic process GO:0008152 IEA
    cell cycle GO:0007049 IEA
    adenylate cyclase-modulating G-protein coupled receptor signaling pathway GO:0007188 IBA
Subcellular Localization
    midbody GO:0030496 ISS
    centrosome GO:0005813 ISS
    heterotrimeric G-protein complex GO:0005834 IBA
    nucleus GO:0005634 IEA
    extracellular exosome GO:0070062 IEA
    lysosomal membrane GO:0005765 IEA
    plasma membrane GO:0005886 ISS
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified GNAI1 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GNAI1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

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