Gene description for GNAS
Gene name GNAS complex locus
Gene symbol GNAS
Other names/aliases GNAS1
Species Bos taurus
 Database cross references - GNAS
ExoCarta ExoCarta_281793
Vesiclepedia VP_281793
Entrez Gene 281793
UniProt P04896   O18979  
 GNAS identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GNAS
Molecular Function
    GTPase activity GO:0003924 IEA
    insulin-like growth factor receptor binding GO:0005159 IEA
    GTP binding GO:0005525 IEA
    G-protein beta/gamma-subunit complex binding GO:0031683 IEA
    beta-2 adrenergic receptor binding GO:0031698 IEA
    D1 dopamine receptor binding GO:0031748 IEA
    mu-type opioid receptor binding GO:0031852 IEA
    ionotropic glutamate receptor binding GO:0035255 IEA
    corticotropin-releasing hormone receptor 1 binding GO:0051430 IEA
Biological Process
    adenylate cyclase-activating dopamine receptor signaling pathway GO:0007191 IEA
    sensory perception of chemical stimulus GO:0007606 IEA
    response to parathyroid hormone GO:0071107 IEA
Subcellular Localization
    heterotrimeric G-protein complex GO:0005834 IEA
 Experiment description of studies that identified GNAS in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GNAS
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GNAS is involved
No pathways found





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