Gene description for PDIA3
Gene name protein disulfide isomerase family A, member 3
Gene symbol PDIA3
Other names/aliases GRP58
Species Bos taurus
 Database cross references - PDIA3
ExoCarta ExoCarta_281803
Entrez Gene 281803
 PDIA3 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PDIA3
Molecular Function
    protein disulfide isomerase activity GO:0003756 IEA
Biological Process
    cell redox homeostasis GO:0045454 IEA
    protein folding GO:0006457 IEA
    positive regulation of apoptotic process GO:0043065 ISS
Subcellular Localization
    melanosome GO:0042470 IEA
    endoplasmic reticulum GO:0005783 ISS
    endoplasmic reticulum lumen GO:0005788 IEA
 Experiment description of studies that identified PDIA3 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PDIA3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PDIA3 is involved
No pathways found





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