Gene description for HSD3B1
Gene name hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Gene symbol HSD3B1
Other names/aliases HSD3B
Species Bos taurus
 Database cross references - HSD3B1
ExoCarta ExoCarta_281824
Entrez Gene 281824
UniProt P14893  
 HSD3B1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for HSD3B1
Molecular Function
    3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 IEA
    steroid delta-isomerase activity GO:0004769 IEA
Biological Process
    oxidation-reduction process GO:0055114 IEA
    steroid biosynthetic process GO:0006694 IEA
Subcellular Localization
    smooth endoplasmic reticulum membrane GO:0030868 IDA
    mitochondrial membrane GO:0031966 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified HSD3B1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HSD3B1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HSD3B1 is involved
PathwayEvidenceSource
Androgen biosynthesis IEA Reactome
Glucocorticoid biosynthesis IEA Reactome
Mineralocorticoid biosynthesis IEA Reactome





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