Gene description for IGF2R
Gene name insulin-like growth factor 2 receptor
Gene symbol IGF2R
Other names/aliases CI-MPR
CIMPR
Species Bos taurus
 Database cross references - IGF2R
ExoCarta ExoCarta_281849
Vesiclepedia VP_281849
Entrez Gene 281849
UniProt P08169  
 IGF2R identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for IGF2R
Molecular Function
    insulin-like growth factor binding GO:0005520 IEA
    D-mannose binding GO:0005537 IEA
    signaling receptor activity GO:0038023 IEA
Biological Process
    lysosomal transport GO:0007041 IEA
Subcellular Localization
    late endosome GO:0005770 IEA
    trans-Golgi network GO:0005802 IEA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified IGF2R in exosomes
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IGF2R
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GGA3  
Reconstituted Complex Bos taurus
2 AP1G1  
Affinity Capture-Western Bos taurus
3 GGA1  
Reconstituted Complex Bos taurus
4 GGA2  
Reconstituted Complex Bos taurus
5 GGA1 26088
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which IGF2R is involved
No pathways found





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