Gene description for ITGB1
Gene name integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
Gene symbol ITGB1
Other names/aliases -
Species Bos taurus
 Database cross references - ITGB1
ExoCarta ExoCarta_281876
Vesiclepedia VP_281876
Entrez Gene 281876
UniProt P53712  
 ITGB1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ITGB1
Molecular Function
    fibronectin binding GO:0001968 IEA
    integrin binding GO:0005178 IEA
    C-X3-C chemokine binding GO:0019960 IEA
    laminin binding GO:0043236 IEA
    collagen binding involved in cell-matrix adhesion GO:0098639 IEA
Biological Process
    cell-matrix adhesion GO:0007160 IEA
    integrin-mediated signaling pathway GO:0007229 IEA
    cell migration GO:0016477 IEA
    cell adhesion mediated by integrin GO:0033627 IEA
Subcellular Localization
    focal adhesion GO:0005925 IEA
    integrin complex GO:0008305 IEA
    cell surface GO:0009986 IEA
 Experiment description of studies that identified ITGB1 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ITGB1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ITGB1 is involved
No pathways found





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