Gene description for ITGB2
Gene name integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
Gene symbol ITGB2
Other names/aliases -
Species Bos taurus
 Database cross references - ITGB2
ExoCarta ExoCarta_281877
Vesiclepedia VP_281877
Entrez Gene 281877
UniProt P32592  
 ITGB2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ITGB2
Molecular Function
    amyloid-beta binding GO:0001540 IEA
    integrin binding GO:0005178 IEA
Biological Process
    cell-matrix adhesion GO:0007160 IEA
    integrin-mediated signaling pathway GO:0007229 IEA
    cell migration GO:0016477 IEA
    cell adhesion mediated by integrin GO:0033627 IEA
Subcellular Localization
    focal adhesion GO:0005925 IEA
    integrin complex GO:0008305 IEA
    cell surface GO:0009986 IEA
 Experiment description of studies that identified ITGB2 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ITGB2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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