Gene description for ITPR2
Gene name inositol 1,4,5-trisphosphate receptor, type 2
Gene symbol ITPR2
Other names/aliases insP3R2
Species Bos taurus
 Database cross references - ITPR2
ExoCarta ExoCarta_281878
Vesiclepedia VP_281878
Entrez Gene 281878
UniProt Q8WN96  
 ITPR2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ITPR2
Molecular Function
    inositol 1,4,5-trisphosphate-gated calcium channel activity GO:0005220 IEA
    inositol 1,4,5 trisphosphate binding GO:0070679 IEA
Biological Process
    calcium ion transmembrane transport GO:0070588 IEA
Subcellular Localization
    endoplasmic reticulum GO:0005783 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified ITPR2 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ITPR2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ITPR2 is involved
No pathways found





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