Gene description for ITPR2
Gene name inositol 1,4,5-trisphosphate receptor, type 2
Gene symbol ITPR2
Other names/aliases insP3R2
Species Bos taurus
 Database cross references - ITPR2
ExoCarta ExoCarta_281878
Entrez Gene 281878
UniProt Q8WN96  
 ITPR2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ITPR2
Molecular Function
    inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity GO:0005220 IEA
Biological Process
    calcium ion transmembrane transport GO:0070588 IEA
    inositol phosphate-mediated signaling GO:0048016 IEA
Subcellular Localization
    transport vesicle membrane GO:0030658 IEA
    secretory granule membrane GO:0030667 IDA
    integral component of membrane GO:0016021 IEA
    endoplasmic reticulum membrane GO:0005789 IEA
    rough endoplasmic reticulum GO:0005791 IDA
 Experiment description of studies that identified ITPR2 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ITPR2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ITPR2 is involved
No pathways found

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