Gene description for LOXL4
Gene name lysyl oxidase-like 4
Gene symbol LOXL4
Other names/aliases -
Species Bos taurus
 Database cross references - LOXL4
ExoCarta ExoCarta_281904
Entrez Gene 281904
UniProt Q8MJ24  
 LOXL4 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for LOXL4
Molecular Function
    copper ion binding GO:0005507 IEA
    protein-lysine 6-oxidase activity GO:0004720 IEA
    scavenger receptor activity GO:0005044 IEA
Biological Process
    receptor-mediated endocytosis GO:0006898 IEA
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    receptor complex GO:0043235 IEA
    extracellular exosome GO:0070062 IEA
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified LOXL4 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LOXL4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LOXL4 is involved
No pathways found

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