Gene description for MYO10
Gene name myosin X
Gene symbol MYO10
Other names/aliases -
Species Bos taurus
 Database cross references - MYO10
ExoCarta ExoCarta_281935
Entrez Gene 281935
UniProt P79114  
 MYO10 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for MYO10
Molecular Function
    actin-dependent ATPase activity GO:0030898 IDA
    plus-end directed microfilament motor activity GO:0060002 IDA
    calmodulin binding GO:0005516 IEA
    actin filament binding GO:0051015 IDA
    phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 IDA
    ATP binding GO:0005524 IEA
Biological Process
    regulation of cell shape GO:0008360 IMP
    metabolic process GO:0008152 IEA
    cytoskeleton-dependent intracellular transport GO:0030705 IDA
    regulation of filopodium assembly GO:0051489 IDA
Subcellular Localization
    cytosol GO:0005829 TAS
    lamellipodium GO:0030027 IDA
    cell cortex GO:0005938 IEA
    filopodium tip GO:0032433 IDA
    filopodium membrane GO:0031527 IEA
    ruffle GO:0001726 IDA
    myosin complex GO:0016459 IEA
 Experiment description of studies that identified MYO10 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MYO10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MYO10 is involved
No pathways found





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