Gene description for PRDX1
Gene name peroxiredoxin 1
Gene symbol PRDX1
Other names/aliases PRX1
Species Bos taurus
 Database cross references - PRDX1
ExoCarta ExoCarta_281997
Entrez Gene 281997
 PRDX1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PRDX1
Molecular Function
    identical protein binding GO:0042802 IEA
    thioredoxin peroxidase activity GO:0008379 IEA
    poly(A) RNA binding GO:0044822 IEA
Biological Process
    natural killer cell mediated cytotoxicity GO:0042267 IEA
    regulation of NF-kappaB import into nucleus GO:0042345 ISS
    removal of superoxide radicals GO:0019430 IEA
    response to oxidative stress GO:0006979 ISS
    cell proliferation GO:0008283 IEA
    regulation of stress-activated MAPK cascade GO:0032872 IEA
    retina homeostasis GO:0001895 IEA
    hydrogen peroxide catabolic process GO:0042744 IEA
    erythrocyte homeostasis GO:0034101 IEA
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
    nucleus GO:0005634 IEA
    extracellular exosome GO:0070062 IEA
    melanosome GO:0042470 IEA
    mitochondrion GO:0005739 IEA
 Experiment description of studies that identified PRDX1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PRDX1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PRDX1 is involved
No pathways found





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