Gene description for TRPC4
Gene name transient receptor potential cation channel, subfamily C, member 4
Gene symbol TRPC4
Other names/aliases -
Species Bos taurus
 Database cross references - TRPC4
ExoCarta ExoCarta_282102
Vesiclepedia VP_282102
Entrez Gene 282102
UniProt P79100  
 TRPC4 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for TRPC4
Molecular Function
    protein binding GO:0005515 IEA
    store-operated calcium channel activity GO:0015279 IEA
    inositol 1,4,5 trisphosphate binding GO:0070679 IEA
Biological Process
    manganese ion transport GO:0006828 IEA
    regulation of cytosolic calcium ion concentration GO:0051480 IEA
    calcium ion transmembrane transport GO:0070588 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    cation channel complex GO:0034703 IEA
 Experiment description of studies that identified TRPC4 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TRPC4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TRPC4 is involved
PathwayEvidenceSource
Ion channel transport IEA Reactome
Stimuli-sensing channels IEA Reactome
Transport of small molecules IEA Reactome
TRP channels IEA Reactome





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