Gene description for YWHAE
Gene name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
Gene symbol YWHAE
Other names/aliases -
Species Bos taurus
 Database cross references - YWHAE
ExoCarta ExoCarta_282125
Entrez Gene 282125
UniProt P62261  
 YWHAE identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for YWHAE
Molecular Function
    potassium channel regulator activity GO:0015459 IEA
    histone deacetylase binding GO:0042826 IEA
    protein domain specific binding GO:0019904 IEA
    MHC class II protein complex binding GO:0023026 IEA
    phosphoserine binding GO:0050815 IEA
    protein heterodimerization activity GO:0046982 IEA
    poly(A) RNA binding GO:0044822 IEA
    ion channel binding GO:0044325 IEA
Biological Process
    regulation of potassium ion transmembrane transporter activity GO:1901016 IEA
    protein targeting GO:0006605 IEA
    cerebral cortex development GO:0021987 IEA
    hippocampus development GO:0021766 IEA
    substantia nigra development GO:0021762 IEA
    negative regulation of peptidyl-serine dephosphorylation GO:1902309 IEA
    neuron migration GO:0001764 IEA
    regulation of membrane repolarization GO:0060306 IEA
Subcellular Localization
    mitochondrion GO:0005739 IEA
    extracellular exosome GO:0070062 IEA
    membrane GO:0016020 IEA
    melanosome GO:0042470 IEA
    focal adhesion GO:0005925 IEA
 Experiment description of studies that identified YWHAE in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for YWHAE
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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