Gene description for ACVR2B
Gene name activin A receptor, type IIB
Gene symbol ACVR2B
Other names/aliases ActR-IIB
ActRIIB
Species Bos taurus
 Database cross references - ACVR2B
ExoCarta ExoCarta_282131
Entrez Gene 282131
UniProt Q95126  
 ACVR2B identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ACVR2B
Molecular Function
    ATP binding GO:0005524 IEA
    metal ion binding GO:0046872 IEA
    receptor signaling protein serine/threonine kinase activity GO:0004702 IEA
    transmembrane receptor protein serine/threonine kinase activity GO:0004675 IEA
Biological Process
    transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 IEA
    signal transduction by protein phosphorylation GO:0023014 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified ACVR2B in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ACVR2B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ACVR2B is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here