Gene description for ADAM10
Gene name	ADAM metallopeptidase domain 10
Gene symbol	ADAM10
Other names/aliases	ADAM 10
Species	Bos taurus
Database cross references - ADAM10
ExoCarta	ExoCarta_282132
Entrez Gene	282132
UniProt	Q10741
ADAM10 identified in exosomes derived from the following tissue/cell type
Milk	23459212

Gene ontology annotations for ADAM10

Molecular Function     SH3 domain binding GO:0017124 IEA     metallopeptidase activity GO:0008237 ISS     protein binding GO:0005515 IPI     protein kinase binding GO:0019901 ISS     metalloendopeptidase activity GO:0004222 ISS     endopeptidase activity GO:0004175 ISS     protein homodimerization activity GO:0042803 ISS     zinc ion binding GO:0008270 IEA Biological Process     positive regulation of cell proliferation GO:0008284 IEA     membrane protein ectodomain proteolysis GO:0006509 ISS     PMA-inducible membrane protein ectodomain proteolysis GO:0051088 IEA     positive regulation of T cell chemotaxis GO:0010820 IEA     constitutive protein ectodomain proteolysis GO:0051089 IEA     Notch signaling pathway GO:0007219 ISS     protein phosphorylation GO:0006468 ISS     response to tumor necrosis factor GO:0034612 IEA     in utero embryonic development GO:0001701 ISS     positive regulation of cell growth GO:0030307 IEA     negative regulation of cell adhesion GO:0007162 ISS     monocyte activation GO:0042117 IEA Subcellular Localization     nucleus GO:0005634 ISS     Golgi membrane GO:0000139 IEA     integral component of membrane GO:0016021 IEA     focal adhesion GO:0005925 IEA     Golgi apparatus GO:0005794 ISS     cell surface GO:0009986 ISS     perinuclear endoplasmic reticulum GO:0097038 IEA     cytoplasm GO:0005737 ISS     postsynaptic density GO:0014069 IEA     tetraspanin-enriched microdomain GO:0097197 IEA     Golgi-associated vesicle GO:0005798 ISS     extracellular exosome GO:0070062 IEA