Gene description for AKR1C4
Gene name aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
Gene symbol AKR1C4
Other names/aliases AKR1C1
Species Bos taurus
 Database cross references - AKR1C4
ExoCarta ExoCarta_282138
Entrez Gene 282138
UniProt P52898  
 AKR1C4 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for AKR1C4
Molecular Function
    oxidoreductase activity GO:0016491 IEA
Biological Process
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified AKR1C4 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for AKR1C4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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