Gene description for ANGPT2
Gene name angiopoietin 2
Gene symbol ANGPT2
Other names/aliases -
Species Bos taurus
 Database cross references - ANGPT2
ExoCarta ExoCarta_282141
Vesiclepedia VP_282141
Entrez Gene 282141
UniProt O77802  
 ANGPT2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ANGPT2
Molecular Function
    receptor tyrosine kinase binding GO:0030971 IEA
Biological Process
    angiogenesis GO:0001525 IEA
    Tie signaling pathway GO:0048014 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
    collagen-containing extracellular matrix GO:0062023 IEA
 Experiment description of studies that identified ANGPT2 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ANGPT2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ANGPT2 is involved
PathwayEvidenceSource
Cell surface interactions at the vascular wall IEA Reactome
Hemostasis IEA Reactome
Tie2 Signaling IEA Reactome





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