Gene description for COL1A2
Gene name collagen, type I, alpha 2
Gene symbol COL1A2
Other names/aliases -
Species Bos taurus
 Database cross references - COL1A2
ExoCarta ExoCarta_282188
Entrez Gene 282188
UniProt P02465  
 COL1A2 identified in exosomes derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for COL1A2
Molecular Function
    SMAD binding GO:0046332 IEA
    metal ion binding GO:0046872 IEA
    extracellular matrix structural constituent GO:0005201 IEA
    identical protein binding GO:0042802 IEA
    platelet-derived growth factor binding GO:0048407 IEA
    protein binding, bridging GO:0030674 IEA
Biological Process
    cellular response to amino acid stimulus GO:0071230 IEA
    regulation of blood pressure GO:0008217 IEA
    skin morphogenesis GO:0043589 IEA
    Rho protein signal transduction GO:0007266 IEA
    protein heterotrimerization GO:0070208 IEA
    skeletal system development GO:0001501 IEA
    blood vessel development GO:0001568 IEA
    collagen fibril organization GO:0030199 IEA
    transforming growth factor beta receptor signaling pathway GO:0007179 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    intracellular GO:0005622 IEA
    collagen type I trimer GO:0005584 IEA
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified COL1A2 in exosomes
1
Experiment ID 187
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COL1A2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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