Gene description for CORO1A
Gene name coronin, actin binding protein, 1A
Gene symbol CORO1A
Other names/aliases -
Species Bos taurus
 Database cross references - CORO1A
ExoCarta ExoCarta_282196
Entrez Gene 282196
UniProt Q92176  
 CORO1A identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CORO1A
Molecular Function
    protein homodimerization activity GO:0042803 IEA
    poly(A) RNA binding GO:0044822 IEA
    actin filament binding GO:0051015 IBA
    protein C-terminus binding GO:0008022 IEA
    phosphatidylinositol 3-kinase binding GO:0043548 IEA
Biological Process
    positive regulation of cell migration GO:0030335 IEA
    leukocyte chemotaxis GO:0030595 IEA
    positive regulation of T cell proliferation GO:0042102 IEA
    regulation of cell shape GO:0008360 IEA
    positive chemotaxis GO:0050918 IEA
    negative regulation of neuron apoptotic process GO:0043524 IEA
    homeostasis of number of cells within a tissue GO:0048873 IEA
    uropod organization GO:0032796 IEA
    regulation of actin filament polymerization GO:0030833 IEA
    phagolysosome assembly GO:0001845 IEA
    nerve growth factor signaling pathway GO:0038180 IEA
    actin filament organization GO:0007015 IEA
    negative regulation of vesicle fusion GO:0031339 IEA
    calcium ion transport GO:0006816 IEA
    cell-substrate adhesion GO:0031589 IEA
    cellular response to interleukin-4 GO:0071353 IEA
    negative regulation of actin nucleation GO:0051126 IEA
    early endosome to recycling endosome transport GO:0061502 IEA
    actin cytoskeleton organization GO:0030036 IBA
    T cell homeostasis GO:0043029 IEA
    regulation of release of sequestered calcium ion into cytosol GO:0051279 IEA
Subcellular Localization
    cell-cell junction GO:0005911 IEA
    lamellipodium GO:0030027 IEA
    actin cytoskeleton GO:0015629 IBA
    cortical actin cytoskeleton GO:0030864 IEA
    extracellular exosome GO:0070062 IEA
    phagocytic vesicle membrane GO:0030670 IEA
    immunological synapse GO:0001772 IEA
    early endosome GO:0005769 IEA
    axon GO:0030424 IEA
    actin filament GO:0005884 IEA
    phagocytic cup GO:0001891 IEA
 Experiment description of studies that identified CORO1A in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CORO1A
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CORO1A is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here