Gene description for CSN1S1
Gene name casein alpha s1
Gene symbol CSN1S1
Other names/aliases CSN1
Species Bos taurus
 Database cross references - CSN1S1
ExoCarta ExoCarta_282208
Vesiclepedia VP_282208
Entrez Gene 282208
UniProt P02662  
 CSN1S1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
Serum 19327352    
 Gene ontology annotations for CSN1S1
Biological Process
    response to estradiol GO:0032355 IEA
    response to progesterone GO:0032570 IEA
    response to dehydroepiandrosterone GO:1903494 IEA
    response to 11-deoxycorticosterone GO:1903496 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified CSN1S1 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 187
MISEV standards
EM
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors "Ochieng J, Pratap S, Khatua AK, Sakwe AM."
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CSN1S1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Cep290  
Affinity Capture-MS Mus musculus
2 IQCB1  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CSN1S1 is involved
PathwayEvidenceSource
Miscellaneous transport and binding events IEA Reactome
Transport of small molecules IEA Reactome





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