Gene description for IGFBP2
Gene name insulin-like growth factor binding protein 2, 36kDa
Gene symbol IGFBP2
Other names/aliases -
Species Bos taurus
 Database cross references - IGFBP2
ExoCarta ExoCarta_282260
Entrez Gene 282260
UniProt P13384  
 IGFBP2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for IGFBP2
Molecular Function
    insulin-like growth factor II binding GO:0031995 ISS
    insulin-like growth factor I binding GO:0031994 ISS
Biological Process
    regulation of insulin-like growth factor receptor signaling pathway GO:0043567 ISS
    response to insulin GO:0032868 IDA
    regulation of cell growth GO:0001558 IEA
    positive regulation of activated T cell proliferation GO:0042104 ISS
Subcellular Localization
    extracellular region GO:0005576 ISS
    extracellular space GO:0005615 ISS
 Experiment description of studies that identified IGFBP2 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IGFBP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which IGFBP2 is involved
No pathways found

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