Gene description for MAN2B1
Gene name mannosidase, alpha, class 2B, member 1
Gene symbol MAN2B1
Other names/aliases MANB
Species Bos taurus
 Database cross references - MAN2B1
ExoCarta ExoCarta_282272
Vesiclepedia VP_282272
Entrez Gene 282272
UniProt Q29451  
 MAN2B1 identified in sEVs derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for MAN2B1
Molecular Function
    alpha-mannosidase activity GO:0004559 IEA
    carbohydrate binding GO:0030246 IEA
Biological Process
    mannose metabolic process GO:0006013 IEA
Subcellular Localization
    lysosome GO:0005764 IEA
 Experiment description of studies that identified MAN2B1 in sEVs
1
Experiment ID 187
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors "Ochieng J, Pratap S, Khatua AK, Sakwe AM."
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MAN2B1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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