Gene description for PGLYRP1
Gene name peptidoglycan recognition protein 1
Gene symbol PGLYRP1
Other names/aliases PGLYRP
Species Bos taurus
 Database cross references - PGLYRP1
ExoCarta ExoCarta_282305
Vesiclepedia VP_282305
Entrez Gene 282305
UniProt Q8SPP7  
 PGLYRP1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PGLYRP1
Molecular Function
    zinc ion binding GO:0008270 IEA
    N-acetylmuramoyl-L-alanine amidase activity GO:0008745 IEA
    peptidoglycan immune receptor activity GO:0016019 IEA
    peptidoglycan binding GO:0042834 IEA
Biological Process
    peptidoglycan catabolic process GO:0009253 IEA
    detection of bacterium GO:0016045 IEA
    innate immune response GO:0045087 IEA
    defense response to Gram-positive bacterium GO:0050830 IEA
 Experiment description of studies that identified PGLYRP1 in exosomes
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PGLYRP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PGLYRP1 is involved
PathwayEvidenceSource
Antimicrobial peptides IEA Reactome
Immune System IEA Reactome
Innate Immune System IEA Reactome
Neutrophil degranulation IEA Reactome





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