Gene description for SLC6A8
Gene name solute carrier family 6 (neurotransmitter transporter), member 8
Gene symbol SLC6A8
Other names/aliases -
Species Bos taurus
 Database cross references - SLC6A8
ExoCarta ExoCarta_282367
Entrez Gene 282367
UniProt O18875  
 SLC6A8 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SLC6A8
Molecular Function
    neurotransmitter:sodium symporter activity GO:0005328 IEA
    creatine:sodium symporter activity GO:0005309 IEA
Biological Process
    neurotransmitter transport GO:0006836 IEA
    creatine transmembrane transport GO:1902598 IEA
    sodium ion transport GO:0006814 IEA
Subcellular Localization
    integral component of plasma membrane GO:0005887 IEA
 Experiment description of studies that identified SLC6A8 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SLC6A8
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC6A8 is involved
PathwayEvidenceSource
Creatine metabolism IEA Reactome





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