Gene description for SLC6A8
Gene name solute carrier family 6 (neurotransmitter transporter), member 8
Gene symbol SLC6A8
Other names/aliases -
Species Bos taurus
 Database cross references - SLC6A8
ExoCarta ExoCarta_282367
Vesiclepedia VP_282367
Entrez Gene 282367
UniProt O18875  
 SLC6A8 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SLC6A8
Molecular Function
    creatine:sodium symporter activity GO:0005309 IEA
Biological Process
    neurotransmitter transport GO:0006836 IEA
    sodium ion transmembrane transport GO:0035725 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified SLC6A8 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SLC6A8
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC6A8 is involved
PathwayEvidenceSource
Creatine metabolism IEA Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome





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