Gene description for PRDX6
Gene name peroxiredoxin 6
Gene symbol PRDX6
Other names/aliases AOP2
Species Bos taurus
 Database cross references - PRDX6
ExoCarta ExoCarta_282438
Vesiclepedia VP_282438
Entrez Gene 282438
UniProt O77834  
 PRDX6 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PRDX6
Molecular Function
    phospholipase A2 activity GO:0004623 IEA
    glutathione peroxidase activity GO:0004602 IEA
    peroxiredoxin activity GO:0051920 IEA
    peroxidase activity GO:0004601 ISS
Biological Process
    oxidation-reduction process GO:0055114 IEA
    response to reactive oxygen species GO:0000302 ISS
    phospholipid catabolic process GO:0009395 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    cytoplasmic membrane-bounded vesicle GO:0016023 IEA
    lysosome GO:0005764 IEA
    cytoplasm GO:0005737 ISS
    extracellular exosome GO:0070062 IEA
    cytosol GO:0005829 ISS
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified PRDX6 in exosomes
1
Experiment ID 213
MISEV standards
✘ EV Biophysical techniques
✘ EV Enriched markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PRDX6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PRDX6 is involved
PathwayEvidenceSource
Detoxification of Reactive Oxygen Species IEA Reactome





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