Gene description for PRDX6
Gene name peroxiredoxin 6
Gene symbol PRDX6
Other names/aliases AOP2
Species Bos taurus
 Database cross references - PRDX6
ExoCarta ExoCarta_282438
Entrez Gene 282438
UniProt O77834  
 PRDX6 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PRDX6
Molecular Function
    phospholipase A2 activity GO:0004623 IEA
    glutathione peroxidase activity GO:0004602 IEA
    peroxiredoxin activity GO:0051920 IEA
    peroxidase activity GO:0004601 ISS
Biological Process
    oxidation-reduction process GO:0055114 IEA
    response to reactive oxygen species GO:0000302 ISS
    phospholipid catabolic process GO:0009395 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    cytoplasmic membrane-bounded vesicle GO:0016023 IEA
    lysosome GO:0005764 IEA
    cytoplasm GO:0005737 ISS
    extracellular exosome GO:0070062 IEA
    cytosol GO:0005829 ISS
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified PRDX6 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PRDX6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PRDX6 is involved
PathwayEvidenceSource
Detoxification of Reactive Oxygen Species IEA Reactome





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