Gene description for PSEN1
Gene name	presenilin 1
Gene symbol	PSEN1
Other names/aliases	-
Species	Bos taurus
Database cross references - PSEN1
ExoCarta	ExoCarta_282705
Vesiclepedia	VP_282705
Entrez Gene	282705
UniProt	Q9XT97
PSEN1 identified in sEVs derived from the following tissue/cell type
Milk	23459212

Gene ontology annotations for PSEN1

Molecular Function     beta-catenin binding GO:0008013 IEA     aspartic endopeptidase activity, intramembrane cleaving GO:0042500 IEA     cadherin binding GO:0045296 IEA Biological Process     membrane protein ectodomain proteolysis GO:0006509 IEA     calcium ion transport GO:0006816 IEA     Notch receptor processing GO:0007220 IEA     protein processing GO:0016485 IEA     intracellular signal transduction GO:0035556 IEA     amyloid precursor protein catabolic process GO:0042987 IEA     negative regulation of apoptotic process GO:0043066 IEA     amyloid-beta metabolic process GO:0050435 IEA     smooth endoplasmic reticulum calcium ion homeostasis GO:0051563 IEA Subcellular Localization     nucleus GO:0005634 IEA     mitochondrial inner membrane GO:0005743 IEA     lysosomal membrane GO:0005765 IEA     endoplasmic reticulum GO:0005783 IEA     cell cortex GO:0005938 IEA     cell surface GO:0009986 IEA     apical plasma membrane GO:0016324 IEA     Z disc GO:0030018 IEA     growth cone GO:0030426 IEA     neuromuscular junction GO:0031594 IEA     ciliary rootlet GO:0035253 IEA     neuronal cell body GO:0043025 IEA     dendritic shaft GO:0043198 IEA     membrane raft GO:0045121 IEA     perinuclear region of cytoplasm GO:0048471 IEA