Gene description for PRLHR
Gene name prolactin releasing hormone receptor
Gene symbol PRLHR
Other names/aliases GPR10
GR3
PrRPR
Species Homo sapiens
 Database cross references - PRLHR
ExoCarta ExoCarta_2834
Vesiclepedia VP_2834
Entrez Gene 2834
HGNC 4464
MIM 600895
UniProt P49683  
 PRLHR identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for PRLHR
Molecular Function
    G protein-coupled receptor activity GO:0004930 TAS
    neuropeptide Y receptor activity GO:0004983 IEA
    protein binding GO:0005515 IPI
    neuropeptide receptor activity GO:0008188 IBA
    neuropeptide binding GO:0042923 IBA
Biological Process
    G protein-coupled receptor signaling pathway GO:0007186 IBA
    neuropeptide signaling pathway GO:0007218 IEA
    female pregnancy GO:0007565 TAS
    feeding behavior GO:0007631 IEA
    hormone metabolic process GO:0042445 IEA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 TAS
    cilium GO:0005929 IDA
    neuron projection GO:0043005 IBA
 Experiment description of studies that identified PRLHR in sEVs
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for PRLHR
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PICK1  
Affinity Capture-Western Homo sapiens
2 GRIP1  
Affinity Capture-Western Homo sapiens
View the network image/svg+xml



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