Gene description for PREP
Gene name prolyl endopeptidase
Gene symbol PREP
Other names/aliases -
Species Bos taurus
 Database cross references - PREP
ExoCarta ExoCarta_286818
Entrez Gene 286818
UniProt Q9XTA2  
 PREP identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PREP
Molecular Function
    serine-type endopeptidase activity GO:0004252 IEA
    serine-type exopeptidase activity GO:0070008 IEA
Biological Process
    proteolysis GO:0006508 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified PREP in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PREP
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PREP is involved
No pathways found





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