Gene description for FTL
Gene name ferritin, light polypeptide
Gene symbol FTL
Other names/aliases -
Species Bos taurus
 Database cross references - FTL
ExoCarta ExoCarta_286861
Entrez Gene 286861
UniProt O46415  
 FTL identified in exosomes derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for FTL
Molecular Function
    iron ion binding GO:0005506 ISS
    ferric iron binding GO:0008199 IEA
Biological Process
    cellular iron ion homeostasis GO:0006879 IEA
    iron ion transport GO:0006826 IEA
Subcellular Localization
    intracellular ferritin complex GO:0008043 ISS
 Experiment description of studies that identified FTL in exosomes
1
Experiment ID 187
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FTL
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FTL is involved
PathwayEvidenceSource
Iron uptake and transport IEA Reactome
Scavenging by Class A Receptors IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here