Gene description for Ugt2b1
Gene name UDP glucuronosyltransferase 2 family, polypeptide B1
Gene symbol Ugt2b1
Other names/aliases 2B1
Udpgtr2
Ugt2b17
Species Rattus norvegicus
 Database cross references - Ugt2b1
ExoCarta ExoCarta_286954
Vesiclepedia VP_286954
Entrez Gene 286954
UniProt P09875  
 Ugt2b1 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Ugt2b1
Molecular Function
    retinoic acid binding GO:0001972 ISO
    UDP-glycosyltransferase activity GO:0008194 IEA
    glucuronosyltransferase activity GO:0015020 IBA
    glucuronosyltransferase activity GO:0015020 IDA
    glucuronosyltransferase activity GO:0015020 IMP
    glucuronosyltransferase activity GO:0015020 ISO
Biological Process
    xenobiotic metabolic process GO:0006805 TAS
    estrogen metabolic process GO:0008210 IDA
    estrogen metabolic process GO:0008210 ISO
    protein glucuronidation GO:0018411 IDA
    protein O-glucuronidation GO:0018412 IDA
    response to lipopolysaccharide GO:0032496 IEP
    cellular glucuronidation GO:0052695 IDA
    cellular glucuronidation GO:0052695 ISO
    biphenyl catabolic process GO:0070980 IDA
    cellular response to ethanol GO:0071361 IEP
    cellular response to growth hormone stimulus GO:0071378 IEP
    cellular response to glucocorticoid stimulus GO:0071385 IEP
    cellular response to testosterone stimulus GO:0071394 IEP
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IEA
 Experiment description of studies that identified Ugt2b1 in sEVs
1
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Ugt2b1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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