Gene description for Trap1
Gene name TNF receptor-associated protein 1
Gene symbol Trap1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Trap1
ExoCarta ExoCarta_287069
Entrez Gene 287069
UniProt Q5XHZ0  
 Trap1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Trap1
Molecular Function
    poly(A) RNA binding GO:0044822 ISS
    protein kinase binding GO:0019901 ISO
    unfolded protein binding GO:0051082 IEA
    ATP binding GO:0005524 IEA
Biological Process
    negative regulation of cellular respiration GO:1901856 ISS
    protein folding GO:0006457 IEA
    negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway GO:1902176 IMP
    translational attenuation GO:0009386 ISO
Subcellular Localization
    mitochondrial intermembrane space GO:0005758 IDA
    extracellular exosome GO:0070062 ISO
    nucleoplasm GO:0005654 ISO
    mitochondrial inner membrane GO:0005743 ISS
    membrane GO:0016020 ISO
    mitochondrial matrix GO:0005759 ISS
    lipid particle GO:0005811 ISS
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Trap1 in exosomes
1
Experiment ID 35
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD81|CD63
EV Membrane markers
HSPA5
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Trap1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Trap1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here