Gene description for Trap1
Gene name TNF receptor-associated protein 1
Gene symbol Trap1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Trap1
ExoCarta ExoCarta_287069
Entrez Gene 287069
UniProt Q5XHZ0  
 Trap1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Trap1
Molecular Function
    poly(A) RNA binding GO:0044822 ISS
    protein kinase binding GO:0019901 ISO
    unfolded protein binding GO:0051082 IEA
    ATP binding GO:0005524 IEA
Biological Process
    negative regulation of cellular respiration GO:1901856 ISS
    protein folding GO:0006457 IEA
    negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway GO:1902176 IMP
    translational attenuation GO:0009386 ISO
Subcellular Localization
    mitochondrial intermembrane space GO:0005758 IDA
    extracellular exosome GO:0070062 ISO
    nucleoplasm GO:0005654 ISO
    mitochondrial inner membrane GO:0005743 ISS
    membrane GO:0016020 ISO
    mitochondrial matrix GO:0005759 ISS
    lipid particle GO:0005811 ISS
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Trap1 in exosomes
1
Experiment ID 35
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD81|CD63
EV Membrane markers
✔
HSPA5
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Trap1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Trap1 is involved
No pathways found





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