Gene description for Ptrf
Gene name polymerase I and transcript release factor
Gene symbol Ptrf
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Ptrf
ExoCarta ExoCarta_287710
Entrez Gene 287710
 Ptrf identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Ptrf
Molecular Function
    rRNA primary transcript binding GO:0042134 ISS
    protein binding GO:0005515 IPI
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    transcription initiation from RNA polymerase I promoter GO:0006361 ISS
    termination of RNA polymerase I transcription GO:0006363 ISS
    regulation of transcription, DNA-templated GO:0006355 IEA
Subcellular Localization
    protein complex GO:0043234 ISO
    endoplasmic reticulum GO:0005783 IEA
    nucleus GO:0005634 ISS
    plasma membrane GO:0005886 ISO
    caveola GO:0005901 ISO
    cytosol GO:0005829 IEA
    membrane raft GO:0045121 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    mitochondrion GO:0005739 ISS
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified Ptrf in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Ptrf
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ptrf is involved
No pathways found





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