Gene description for Ptrf
Gene name polymerase I and transcript release factor
Gene symbol Ptrf
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Ptrf
ExoCarta ExoCarta_287710
Vesiclepedia VP_287710
Entrez Gene 287710
 Ptrf identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Ptrf
Molecular Function
    protein binding GO:0005515 IPI
    rRNA primary transcript binding GO:0042134 IBA
    rRNA primary transcript binding GO:0042134 ISO
    rRNA primary transcript binding GO:0042134 ISS
    identical protein binding GO:0042802 ISO
Biological Process
    transcription initiation at RNA polymerase I promoter GO:0006361 IBA
    transcription initiation at RNA polymerase I promoter GO:0006361 ISO
    transcription initiation at RNA polymerase I promoter GO:0006361 ISS
    termination of RNA polymerase I transcription GO:0006363 IBA
    termination of RNA polymerase I transcription GO:0006363 ISO
    termination of RNA polymerase I transcription GO:0006363 ISO
    termination of RNA polymerase I transcription GO:0006363 ISS
    rRNA transcription GO:0009303 ISO
    rRNA transcription GO:0009303 ISS
    protein secretion GO:0009306 ISO
    positive regulation of cell motility GO:2000147 ISO
    positive regulation of cell motility GO:2000147 ISS
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
    mitochondrion GO:0005739 ISO
    mitochondrion GO:0005739 ISS
    endoplasmic reticulum GO:0005783 ISO
    cytosol GO:0005829 IEA
    plasma membrane GO:0005886 ISO
    caveola GO:0005901 IBA
    caveola GO:0005901 IDA
    caveola GO:0005901 IEA
    caveola GO:0005901 ISO
    protein-containing complex GO:0032991 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    membrane raft GO:0045121 ISO
 Experiment description of studies that identified Ptrf in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Ptrf
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ptrf is involved
No pathways found





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