Gene description for Psme3
Gene name proteasome (prosome, macropain) activator subunit 3
Gene symbol Psme3
Other names/aliases Ab2-371
Species Rattus norvegicus
 Database cross references - Psme3
ExoCarta ExoCarta_287716
Vesiclepedia VP_287716
Entrez Gene 287716
 Psme3 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Psme3
Molecular Function
    p53 binding GO:0002039 ISO
    copper ion binding GO:0005507 IEA
    primary methylamine oxidase activity GO:0008131 IEA
    identical protein binding GO:0042802 ISO
    quinone binding GO:0048038 IEA
    endopeptidase activator activity GO:0061133 ISO
    MDM2/MDM4 family protein binding GO:0097371 ISO
Biological Process
    amine metabolic process GO:0009308 IEA
    regulation of proteasomal protein catabolic process GO:0061136 ISO
    negative regulation of extrinsic apoptotic signaling pathway GO:2001237 ISO
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    cytosol GO:0005829 ISO
    proteasome activator complex GO:0008537 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified Psme3 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Psme3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Rad23b  
Affinity Capture-MS Rattus norvegicus
2 Map3k3  
Two-hybrid Rattus norvegicus
Affinity Capture-Western Rattus norvegicus
Biochemical Activity Rattus norvegicus
Two-hybrid Rattus norvegicus
3 Psmc3 29677
Co-fractionation Rattus norvegicus
4 Braf  
Two-hybrid Rattus norvegicus
View the network image/svg+xml
 Pathways in which Psme3 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here