Gene description for Psme3
Gene name proteasome (prosome, macropain) activator subunit 3
Gene symbol Psme3
Other names/aliases Ab2-371
Species Rattus norvegicus
 Database cross references - Psme3
ExoCarta ExoCarta_287716
Vesiclepedia VP_287716
Entrez Gene 287716
 Psme3 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Psme3
Molecular Function
    p53 binding GO:0002039 ISO
    copper ion binding GO:0005507 IEA
    primary methylamine oxidase activity GO:0008131 IEA
    identical protein binding GO:0042802 ISO
    quinone binding GO:0048038 IEA
    endopeptidase activator activity GO:0061133 ISO
    MDM2/MDM4 family protein binding GO:0097371 ISO
Biological Process
    amine metabolic process GO:0009308 IEA
    regulation of proteasomal protein catabolic process GO:0061136 ISO
    negative regulation of extrinsic apoptotic signaling pathway GO:2001237 ISO
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    cytosol GO:0005829 ISO
    proteasome activator complex GO:0008537 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified Psme3 in exosomes
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Psme3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Rad23b  
Affinity Capture-MS Rattus norvegicus
2 Map3k3  
Two-hybrid Rattus norvegicus
Affinity Capture-Western Rattus norvegicus
Biochemical Activity Rattus norvegicus
Two-hybrid Rattus norvegicus
3 Psmc3 29677
Co-fractionation Rattus norvegicus
4 Braf  
Two-hybrid Rattus norvegicus
View the network image/svg+xml
 Pathways in which Psme3 is involved
No pathways found





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