Gene description for Psme3
Gene name proteasome (prosome, macropain) activator subunit 3
Gene symbol Psme3
Other names/aliases Ab2-371
Species Rattus norvegicus
 Database cross references - Psme3
ExoCarta ExoCarta_287716
Entrez Gene 287716
 Psme3 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Psme3
Molecular Function
    p53 binding GO:0002039 IEA
    peptidase activity GO:0008233 IEA
    endopeptidase activator activity GO:0061133 IEA
    MDM2/MDM4 family protein binding GO:0097371 IEA
Biological Process
    proteolysis GO:0006508 IEA
    positive regulation of endopeptidase activity GO:0010950 IEA
    regulation of proteasomal protein catabolic process GO:0061136 IEA
    negative regulation of extrinsic apoptotic signaling pathway GO:2001237 IEA
Subcellular Localization
    proteasome activator complex GO:0008537 IEA
    cytoplasm GO:0005737 IEA
    membrane GO:0016020 IEA
    nucleoplasm GO:0005654 IEA
 Experiment description of studies that identified Psme3 in exosomes
Experiment ID 225
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Psme3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Psme3 is involved
No pathways found

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