Gene description for Nvl
Gene name nuclear VCP-like
Gene symbol Nvl
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Nvl
ExoCarta ExoCarta_289323
Entrez Gene 289323
 Nvl identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Nvl
Molecular Function
    ATP binding GO:0005524 IEA
    poly(A) RNA binding GO:0044822 ISO
Subcellular Localization
    membrane GO:0016020 ISO
    cytoplasm GO:0005737 ISO
    mitochondrion GO:0005739 ISO
    plasma membrane GO:0005886 ISO
    nucleus GO:0005634 ISO
    nucleolus GO:0005730 ISO
 Experiment description of studies that identified Nvl in exosomes
1
Experiment ID 93
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [MALDI TOF]
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Nvl
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nvl is involved
No pathways found





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