Gene description for Lrrc8c |
Gene name |
leucine rich repeat containing 8 family, member C |
Gene symbol |
Lrrc8c |
Other names/aliases |
RGD1306585 |
Species |
Rattus norvegicus |
Database cross references - Lrrc8c |
ExoCarta |
ExoCarta_289443 |
Entrez Gene |
289443 |
UniProt |
Q498T9
|
Lrrc8c identified in exosomes derived from the following tissue/cell type |
Reticulocytes
|
21828046
|
Reticulocytes
|
21828046
|
Gene ontology annotations for Lrrc8c |
|
Experiment description of studies that identified Lrrc8c in exosomes |
1 |
Experiment ID |
90 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
HSC70|HSP90|TSG101
|
EV Cytosolic markers |
✔
MHCI
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry [Orbitrap]
|
PubMed ID |
21828046
|
Organism |
Rattus norvegicus |
Experiment description |
The proteo-lipidic composition of exosomes changes during reticulocyte maturation. |
Authors |
Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E |
Journal name |
JBC
|
Publication year |
2011 |
Sample |
Reticulocytes |
Sample name |
Reticulocytes - D2 Rep 1 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
1.16-1.21 g/mL
|
Molecules identified in the study |
Protein Lipids |
Methods used in the study |
Mass spectrometry [QSTAR] Mass spectrometry [Orbitrap] Western blotting |
|
|
2 |
Experiment ID |
96 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|HSP90|HSC70
|
EV Cytosolic markers |
✔
MHCI
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry [Orbitrap]
|
PubMed ID |
21828046
|
Organism |
Rattus norvegicus |
Experiment description |
The proteo-lipidic composition of exosomes changes during reticulocyte maturation. |
Authors |
Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E. |
Journal name |
JBC
|
Publication year |
2011 |
Sample |
Reticulocytes |
Sample name |
Reticulocytes - D2 Rep 2 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
1.16-1.21 g/mL
|
Molecules identified in the study |
Protein Lipids |
Methods used in the study |
Mass spectrometry [QSTAR] Mass spectrometry [Orbitrap] Western blotting |
|
|
Protein-protein interactions for Lrrc8c |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which Lrrc8c is involved |
No pathways found
|
|
|