Gene description for Hsd17b11
Gene name hydroxysteroid (17-beta) dehydrogenase 11
Gene symbol Hsd17b11
Other names/aliases Dhrs8
Species Rattus norvegicus
 Database cross references - Hsd17b11
ExoCarta ExoCarta_289456
Entrez Gene 289456
UniProt Q6AYS8  
 Hsd17b11 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Hsd17b11
Molecular Function
    steroid dehydrogenase activity GO:0016229 ISO
Biological Process
    oxidation-reduction process GO:0055114 IEA
    androgen catabolic process GO:0006710 ISO
    steroid biosynthetic process GO:0006694 IEA
Subcellular Localization
    cytoplasm GO:0005737 ISO
    extracellular region GO:0005576 IEA
    lipid particle GO:0005811 ISO
 Experiment description of studies that identified Hsd17b11 in exosomes
1
Experiment ID 35
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD81|CD63
EV Membrane markers
HSPA5
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Hsd17b11
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hsd17b11 is involved
No pathways found





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