|
 Gene description for Cndp2 |
| Gene name |
CNDP dipeptidase 2 (metallopeptidase M20 family) |
| Gene symbol |
Cndp2 |
| Other names/aliases |
- |
| Species |
Rattus norvegicus |
| Database cross references - Cndp2 |
| ExoCarta |
ExoCarta_291394 |
| Vesiclepedia |
VP_291394 |
| Entrez Gene |
291394 |
| UniProt |
Q6Q0N1
|
| Cndp2 identified in sEVs derived from the following tissue/cell type |
|
Pancreatic cancer cells
|
20124479
|
|
Pancreatic cancer cells
|
20124479
|
|
Urine
|
20535238
|
| Gene ontology annotations for Cndp2 |
|
|
| Experiment description of studies that identified Cndp2 in sEVs |
| 1 |
| Experiment ID |
92 |
| MISEV standards |
|
✔
EM
|
Biophysical techniques |
|
✔
HSP70|GAPDH|CD9|CD151
|
Enriched markers |
|
✘
|
Negative markers |
|
✘
|
Particle analysis
|
|
| Identified molecule |
mrna
|
| Identification method |
Microarray
|
| PubMed ID |
20124479
|
| Organism |
Rattus norvegicus |
| Experiment description |
Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. |
| Authors |
"Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M." |
| Journal name |
CR
|
| Publication year |
2010 |
| Sample |
Pancreatic cancer cells |
| Sample name |
AS |
| Isolation/purification methods |
Differential centrifugation
Sucrose density gradient |
| Flotation density |
1.14-1.17 g/mL
|
| Molecules identified in the study |
Protein
mRNA |
| Methods used in the study |
RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF] |
|
|
| 2 |
| Experiment ID |
93 |
| MISEV standards |
|
✔
EM
|
Biophysical techniques |
|
✔
HSP70|GAPDH|CD9|CD151
|
Enriched markers |
|
✘
|
Negative markers |
|
✘
|
Particle analysis
|
|
| Identified molecule |
mrna
|
| Identification method |
Microarray
|
| PubMed ID |
20124479
|
| Organism |
Rattus norvegicus |
| Experiment description |
Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. |
| Authors |
"Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M." |
| Journal name |
CR
|
| Publication year |
2010 |
| Sample |
Pancreatic cancer cells |
| Sample name |
AS-Tspan8 |
| Isolation/purification methods |
Differential centrifugation
Sucrose density gradient |
| Flotation density |
1.14-1.17 g/mL
|
| Molecules identified in the study |
Protein
mRNA |
| Methods used in the study |
RT-PCR
Western blotting |
|
|
| 3 |
| Experiment ID |
192 |
| MISEV standards |
|
✔
CEM
|
Biophysical techniques |
|
✔
TSG101|HSP70|CD63|CD81|FLOT
|
Enriched markers |
|
✘
|
Negative markers |
|
✘
|
Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
20535238
|
| Organism |
Rattus norvegicus |
| Experiment description |
Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. |
| Authors |
"Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M." |
| Journal name |
Proteomics Clin Appl
|
| Publication year |
2010 |
| Sample |
Urine |
| Sample name |
Urine - Rats of liver injury |
| Isolation/purification methods |
Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| Protein-protein interactions for Cndp2 |
|
|
| Pathways in which Cndp2 is involved |
|
|
|
