Gene description for Pgrmc1
Gene name progesterone receptor membrane component 1
Gene symbol Pgrmc1
Other names/aliases 25-Dx
25Dx
MPR
VEMA
Species Rattus norvegicus
 Database cross references - Pgrmc1
ExoCarta ExoCarta_291948
Entrez Gene 291948
UniProt P70580  
 Pgrmc1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Pgrmc1
Molecular Function
    steroid binding GO:0005496 IEA
    heme binding GO:0020037 IBA
Biological Process
    axon guidance GO:0007411 IEP
Subcellular Localization
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 IEA
    endomembrane system GO:0012505 IBA
    extracellular exosome GO:0070062 ISO
    nucleolus GO:0005730 ISO
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 ISO
 Experiment description of studies that identified Pgrmc1 in exosomes
1
Experiment ID 35
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD81|CD63
EV Membrane markers
HSPA5
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Pgrmc1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pgrmc1 is involved
No pathways found





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